Ilium Trisoprim-480

Injection

Actions
Bactericidal in action with broad spectrum activity. The combination attacks bacterial protein synthesis at two points. It works by sequential blockade, which enhances the individual anti-bacterial effects, so the combination becomes bactericidal. TRISOPRIM is highly active against both Gram-positive and Gram-negative bacteria including many strains which are resistant to commonly used antibiotics. Most B-lactamase producing bacteria are sensitive to TRISOPRIM. Importantly, the synergism of these two components allows lower doses to be used, which reduces the possibility of side affects while still providing optimum cover. Its synergistic effects against a large range of Gram-positive and Gram-negative bacteria includes E-coli, Salmonella and Staphylococci.

TRISOPRIM is rapidly absorbed and quickly distributed producing high concentrations throughout the animal’s body. Its high tissue levels are effective in bacterial infections of the respiratory, alimentary, the urinary and genital tracts, the eyes and ears.

Indications
For the systemic treatment of bacterial infections caused by organisms sensitive to trimethoprim and sulphadiazine in cattle, horses, sheep and pigs.

Directions for use
Shake well before use.
1.0mL to 1.5mL per 30kg bodyweight i.m. daily.

Presentation
Injection 100mL, 250mL glass, 100mL PET, 250mL HDPE.

Composition
Sulphadiazine 400mg/mL,
Trimethoprim 80mg/mL.

Contraindications
Known sulfonamide sensitivity. Parenchymal hepatic damage. Blood dyscrasias.

Precautions
Very occasional localised swelling of a temporary nature may be observed.

Withholding periods
Cattle, sheep, pigs: meat – 28 days
Horses: meat 28 days.
Milk – Milk collected from animals within 36 hours (single dose) or 72 hours (multiple dose) following treatment must not be used for human consumption or processing.

Storage
Store below 25ºC (air conditioning). Protect from light.

Registration
All states

APVMA Number
51143