Aminoglycoside with bactericidal action. It interferes with the protein synthesis of the cell membrane. Absorption is rapid; intramuscular injection reaches peak level at 1 hour. Initially therapeutic blood levels last about 12 hours. After 1 - 2 days, blood levels may be maintained for 24 hours with a single dose. In humans it is 40% bound to plasma protein. Higher tissue levels are reached than plasma levels compared with other aminoglycosides. Gentamicin selectively distributes to kidney in high levels. Distribution to CNS is fair. Excretion is almost unchanged in urine. Gentamicin is highly synergistic with the cephalosporins.
For the control of Gentamicin - susceptible bacterial infections in dogs, cats and horses.
Directions for use
Dogs & Cats: 4.4mg/kg i.m. or s.c. 12 hourly on the first day then once daily. In life threatening infections use this dose every 8 hours.
Horses: Parenteral: 2.0mg/kg bodyweight three times daily by i.v. or i.m. injection.
Intrauterine infusion: 40-50mL diluted with 200-300mL of sterile saline. Use aseptic technique. Infuse daily for 3 – 5 days
Gentam 100mL Injection
Gentamicin 50mg/mL (as Gentamicin Sulphate).
Do not use this product in pregnant animals.
Not to be used unless sensitivity testing indicates other antibiotics are ineffective. Not to be used in animals producing food for human consumption.
Meat – Not to be used in horses that may be slaughtered for human consumption.
Store below 25ºC (air conditioning). Protect from light.